Description: A memorandum by Benjamin Worsley to William, Lord Willoughby of Parnham, dated 22 January 1668; copied by Locke at an unknown date into his “Adversaria 1661” commonplace book, with the marginal caption “Sena”. During the 1660s, Worsley experimented with the cultivation of senna, a plant used as a laxative, in the Caribbean colonies. This memorandum was addressed to Lord Willoughby, governor of Barbados and the Leeward Islands, and was part of an effort to secure a royal patent for the project. See also Worsley’s paper headed “Severall reasons humbly tendered to the Honourable the Attorney Generall for the encourageing of the plantation of senna by a pattent or by an act of parliament” (ca. March 1668) [National Archives, CO 1/20, f. 283]. Locke’s interest was presumably related to his role with the Council of Trade and Plantations.

Publications: None

Discussions: Leng, Benjamin Worsley, 143-146, 148, 205.

Papers relating to Lord Ashley’s case (May-November 1668, April 1669, January 1671)

Location: Public Record Office, London, PRO 30/24/47/2, ff. 1-30.

Description: In late May 1668, Lord Ashley developed an abscess over his liver. The modern diagnosis is a hydatid cyst, a parasitic form of tapeworm. On June 12, he underwent an operation to drain the abscess; he suffered relapses in July and again in September. Lord Ashley consulted a number of physicians during his illness; after the operation, he circulated a set of queries dealing with the advisability of letting the wound heal and of leaving in place a silver tube to allow the abscess to drain. While Locke was neither the surgeon nor the physician in charge of the case, he was responsible for monitoring the patient’s condition, recording detailed observations, and caring for the patient during his convalescence; among others, he advised leaving the silver tube in place. Ashley credited Locke with saving his life.

A full set of documents relating to the case survive in the Shaftesbury papers. These have been collected at the beginning of PRO 30/24/47/2 and are separately described below. The case file concludes with letters from and to the French physician de Briolay de Beaupreau, dating from April 1669 and January 1671, respectively. Note that the volume has been rearranged, and citations by earlier authors may not correspond to the current foliation.

Lord Ashley’s case: Locke’s case notes (June-November 1668)

Location: Public Record Office, London, PRO 30/24/47/2, ff. 19-30.

Description: Extensive notes on Lord Ashley’s case in Latin and in Locke’s hand, covering the period from June 11 through November 3, 1668. The notes begin with a description of the onset of the illness, written in the past tense; beginning on June 11 observations are recorded daily; it is therefore likely that Locke began the document about this date. In addition to the regular observations of the patient’s condition, there are scattered some 13 medical receipts.

The manuscript consists of three gatherings each made up of two sheets of paper folded once to form 4 leaves. Most pages have the header “Obs. 68”; the month often appears in the top left margin. The following marginal captions appear in the left margin: “Abscessus hepatis” (f. 19^r); “Injectio” (f. 21^r); “Fotus” (f. 21^v); “Traumaticum” (f. 21^v); “Cordiale” (f. 22^r). The endorsement “Abscessus” in Locke’s hand appears on f. 30^v. Note that the contents of PRO 30/24/47/2 have been rearranged; this document was previously ff. 68-79.

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):404-449. – The Latin text appears on the even pages, an English translation on the odd pages.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #1 above, pages 394-395, 404.

Lord Ashley’s case: Sir George Ent’s case notes (12 June-25 July 1668)

Location: Public Record Office, London, PRO 30/24/47/2, ff. 1-2.

Description: Case notes on Lord Ashley’s case in English, similar to Locke’s notes, but based on independent observations. The hand has been identified [Olivia Smith, Lives, letters, bodies (2009), page 35] as that of Sir George Ent (1604-1689), a prominent member of the Council of the College of Pysicians. The notes cover the period from Ashley’s operation (June 12) through July 25. The manuscript appears “to have been written at one sitting”, but to be based on “rough notes made as events unfolded“ [Anstey & Principe].

The manuscript consists of a single sheet of paper (290 × 205 mm) folded once to form 2 leaves. Locke’s endorsement appears on f 2^v: “Abscessus Lord Ashleys case journall 68.”

Publications:

“An address on John Locke as a physician : delivered before the Students’ Societies of the Medical Department of the University of Pennsylvania, on Jan. 16th, 1900” / by William Osler. // IN: Lancet. – 20 Oct. 1900:1118-1119.
“John Locke as a physician.” // IN: An Alabama student : and other biographical essays / by William Osler. – New York : Oxford University Press, 1908. – pages 85-89.
A Locke miscellany … / edited by Jean S. Yolton (1990). – pages 103-107.
“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):450-454.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #4 above, pages 395-396, 450.

Lord Ashley’s case: Locke’s case report [late 1668/early 1669]

Location: Public Record Office, London, PRO 30/24/47/2, ff. 14-15.

Description: After Lord Ashley’s recovery – late in 1668 or early the following year – Locke composed a Latin case report which was enclosed in a letter to de Briolay de Beaupreau. A copy of the letter in Locke’s hand is preserved in PRO 30/2/47/2, f. 18. Locke’s report was clearly a retrospective account, written “in a rhetorically self-conscious Latin style” [Anstey & Principe].

The recipient of Locke’s report is a French physician that Locke refers to in the endorsement of the letter as “Monsieur l’Abbé de Beaupreau A Angers”. His memorandum book for 1669 [British Library, Add. MS. 46,470, f. 1] makes the same reference in a note dated 1 June 1669. The letter’s endorsement includes the date “68” De Briolay replied in a letter to a Mr. Browne [possibly Edward Browne, son of Sir Thomas Browne] in April 1669.

The manuscript consists of a single sheet of paper folded once to form 2 leaves. The title “Casus nobilissimi viri domini Antonii Ashley Baronis de Winburne S^t. Giles &c.” appears at the top of the first page (f. 14^r). Endorsements by Locke appear on f 14^v, vertically in the left margin: “Lord Ashleys case 68 Abscessus” and on f 15^v, upside down in the lower margin in partially legible pencil: “Dr. Sidenham [illegible] Medical P^rs [illegible]”. Note that the contents of PRO 30/24/47/2 have been rearranged; this document was previously ff. 3-4.

Publications:

[incomplete English translation]: “An address on John Locke as a physician : delivered before the Students’ Societies of the Medical Department of the University of Pennsylvania, on Jan. 16th, 1900” / by William Osler. // IN: Lancet. – 20 Oct. 1900:1117-1118.
[incomplete English translation]: “John Locke as a physician.” // IN: An Alabama student : and other biographical essays / by William Osler. – New York : Oxford University Press, 1908. – pages 82-84.
[incomplete English translation]: A Locke miscellany … / edited by Jean S. Yolton (1990). – pages 100-103.
“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):456-471. – The Latin text appears on the even pages, an English translation on the odd pages; includes the cover letter.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #4 above, pages 396-397, 456.

Lord Ashley’s case: Lord Ashley’s queries [September 1668]

Location: Public Record Office, London, PRO 30/24/47/2, f. 81^r;
copy in Public Record Office, London, PRO 30/24/47/2, f. 16^r

Description: Lord Ashley suffered a relapse in mid-September, which resulted in further flow from the cyst through a pipe left in the open wound. “Ashley was clearly very concerned about the dangers of living with an open wound in his side, and had a set of twelve questions drafted and distributed to various physicians for their advice” [Anstey & Principe, 386] as to whether to allow the wound to heal and whether the pipe should remain.

Two copies of the queries survive, each attached to a set of responses. One (f. 81^r) is a scribal copy with answers from Sir George Ent (f. 82^r). The other copy (f. 16^r) is in Locke’s hand with answers from Dr. John Micklethwaite (f. 17^r).

The queries (scribal copy) are written on the first page of a single sheet of paper (338 × 230 mm) folded once to form 2 leaves; Ent’s answers are written on the third page (f. 82^r).

Publications:

“An address on John Locke as a physician : delivered before the Students’ Societies of the Medical Department of the University of Pennsylvania, on Jan. 16th, 1900” / by William Osler. // IN: Lancet. – 20 Oct. 1900:1119.
“John Locke as a physician.” // IN: An Alabama student : and other biographical essays / by William Osler. – New York : Oxford University Press, 1908. – pages 89-90.
A Locke miscellany … / edited by Jean S. Yolton (1990). – pages 108-109.
“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):472-473.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #4 above, pages 386, 397, 472.

Lord Ashley’s case: Dr. Francis Glisson’s answers to Lord Ashley’s queries (26 September 1668)

Location: Public Record Office, London, PRO 30/24/47/2, f. 3^r

Description: Answers to Lord Ashley’s queries from Dr. Francis Glisson, in his hand, dated 26 September 1668. The paper is headed “An aunswere to the Quaeryes proposed. Septemb. 26^o 1668.” and endorsed by Locke “Abscessus Concilium Dr Glisson 68”.

Dr. Francis Glisson (1597-1677) was a Fellow of the Royal College of Physicians and an expert on the anatomy of the liver; he served as physician to the Ashley Cooper family and supervised the operation on Lord Ashley’s cyst. His answers to the queries indicate that he had recently examined the wound.

Glisson’s answers are written on the recto of a single sheet of paper (322 × 211 mm).

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):474-476.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #1 above, pages 387, 398, 474.

Lord Ashley’s case: Sir George Ent’s answers to Lord Ashley’s queries [1668]

Location: Public Record Office, London, PRO 30/24/47/2, f. 82^r

Description: Answers to Lord Ashley’s queries from Sir George Ent, in his hand; it was probably written ca. October 1668. The paper was endorsed by Locke, but the endorsement is damaged: “[Ashle]y [E]nt”.

The manuscript consists of a single sheet of paper (338 × 230 mm) folded once to form 2 leaves; a scribal copy of Lord Ashley’s queries is written on the first recto (f. 81^r); Ent’s answers are written on the second recto (f. 82^r).

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):477-478.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #1 above, pages 398, 477.

Lord Ashley’s case: Dr. Timothy Clarke’s answers to Lord Ashley’s queries [1668]

Location: Public Record Office, London, PRO 30/24/47/2, ff. 8-9.

Description: Answers to Lord Ashley’s queries, signed Tim: Clarke (on f. 9^r); it was probably written ca. October 1668. The paper was endorsed by Locke (f. 9^v: “Abscessus Concilium Dr Clark 68”.

The manuscript consists of a single sheet of paper (299 × 190 mm) folded once to form 2 leaves. Clarke’s answers occupy the first three pages; f. 9^v is blank except for Locke’s endorsement.

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):479-480.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #1 above, pages 398, 479.

Lord Ashley’s case: Dr. John Micklethwaite’s answers to Lord Ashley’s queries [1668]

Location: Public Record Office, London, PRO 30/24/47/2, f. 17^r

Description: Answers to Lord Ashley’s queries from Dr. John Micklethwaite, in his hand; it was probably written ca. October 1668. The paper was endorsed by Locke on f. 17^v: “Consilium Abscessus Dr Micklethwaite 68”.

The manuscript consists of a single sheet of paper folded once to form 2 leaves; a copy of Lord Ashley’s queries is written in Locke’s hand on the first recto (f. 16^r); Micklethwaite’s answers are written on the second recto (f. 17^r).

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):481-482.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #1 above, pages 398, 481.

Lord Ashley’s case: Dr. Thomas Sydenham’s advice to Lord Ashley [1668]

Location: Public Record Office, London, PRO 30/24/47/2, ff. 10-11.

Description: Advice on Lord Ashley’s case from Dr. Thomas Sydenham, in his hand; it was probably written ca. October 1668. The paper was endorsed by Locke on f. 11^v: “Consilium Abscessus Dr Sydenham 68”.

Sydenham’s advice to Lord Ashley is the first known connection between Sydenham and Ashley. The paper contains corrections by Locke, which may indicate that it was Locke who consulted Sydenham on the case. However, a year or two later, Sydenham could claim to have treated members of the Ashley household.

Sydenham’s advice is followed by two recipes, headed “The Stronger Liquor” (f. 10^v) and “The Smaller Liquor” (f. 11^r), respectively.

The manuscript consists of a single sheet of paper (306 × 190 mm) folded once to form 2 leaves; f. 11^v is blank, except for Locke’s endorsement.

Publications:

“An address on John Locke as a physician : delivered before the Students’ Societies of the Medical Department of the University of Pennsylvania, on Jan. 16th, 1900” / by William Osler. // IN: Lancet. – 20 Oct. 1900:1120. – Does not include the recipes.
“John Locke as a physician.” // IN: An Alabama student : and other biographical essays / by William Osler. – New York : Oxford University Press, 1908. – pages 92-94. – Does not include the recipes.
A Locke miscellany … / edited by Jean S. Yolton (1990). – pages 100-103. – Does not include the recipes.
Dr. Thomas Sydenham (1624-1689), his life and original writings / Kenneth Dewhurst. – London : Wellcome Historical Medical Library, 1966. – pages 164-166.
“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):483-485.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #5 above, pages 398-399, 481.

Lord Ashley’s case: Locke’s answers to Lord Ashley’s queries [1668]

Location: Public Record Office, London, PRO 30/24/47/2, ff. 12-13.

Description: Locke’s answers to Lord Ashley’s queries, in his own hand; it was probably written ca. October 1668. The paper was endorsed by Locke on f. 13^v: “JL 68”.

The manuscript consists of a single sheet of paper (291 × 203 mm) folded once to form 2 leaves; f. 13 is blank, except for Locke’s endorsement.

Publications:

“An address on John Locke as a physician : delivered before the Students’ Societies of the Medical Department of the University of Pennsylvania, on Jan. 16th, 1900” / by William Osler. // IN: Lancet. – 20 Oct. 1900:1119-1120.
“John Locke as a physician.” // IN: An Alabama student : and other biographical essays / by William Osler. – New York : Oxford University Press, 1908. – pages 90-92.
A Locke miscellany … / edited by Jean S. Yolton (1990). – pages 109-111. – Does not include the recipes.
“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):486-488.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #5 above, pages 398, 486.

Letter from Sir Thomas Strickland to Sir Gilbert Talbot 26 October 1668

Location: Public Record Office, London, PRO 30/24/47/2, ff. 4-5.

Description: A letter from Thomas Strickland dated “Oct. 26^th [1668]”, describing the case of a man with what was probably a hydatid cyst. Sir Gilbert Talbot was presumably making inquiries on Lord Ashley’s behalf.

The manuscript consists of a single sheet, folded to form two leaves, 305 × 194 mm. The letter is addressed “This For his esteemed frind Sir Gilbert Talbott att Whitthall”; endorsed (in Locke’s hand) “Abscessus Tumor latens 68”. The letter is written on f. 4^r; ff. 4^v-5^r are blank; f. 5^v contains the address and Locke’s endorsement.

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):489-490.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #5 above, pages 399, 489.

Letter from Thomas Bankes 6 November 1668

Location: Public Record Office, London, PRO 30/24/47/2, f. 7.

Description: A letter dated “Novemb. 6^th 68” and signed “Tho Bankes”, describing the case of James Oddye, a patient with a hydatid cyst, similar to Lord Ashley’s. The letter is headed “A particuler of the infirmaty or desease of James Oddye of Help[er]by in the Countye of yorke[,] Glover then aged aboute forty yeares” and is endorsed (in Locke’s hand) “Ascessus Oddies Case 68”. Reported to the Royal Society by Sir Paul Neile on 12 November 1668 (Birch, History of the Royal Society 2:321).

The manuscript consists of a single sheet, 315 × 200 mm. Locke’s endorsement appears on the verso.

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):492-493.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #5 above, pages 399, 492.

Letter from John Arnold to [Lord Ashley?] 24 November 1668

Location: Public Record Office, London, PRO 30/24/47/2, f. 6.

Description: A letter signed “Jo: Arnold” to an unidentified correspondent, perhaps Lord Ashley, dated “York 24. of 9^ber [1668]”, describing the case of Mr. Pawson, who probably did not suffer from a hydatid cyst.

The manuscript consists of a single sheet, folded to form two leaves, 300 × 196 mm. The letter is endorsed (in Locke’s hand) “Abscessus Pausons Case 68”. The letter is written on f. 6^r; f. 6^v contains only the endorsement.

Publications:

“John Locke and the case of Anthony Ashley Cooper” / Peter R. Anstey & Lawrence M. Principe. // IN: Early science and medicine. — 16 (2011):491.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)

Discussions: Anstey & Principe, Publication #5 above, pages 399, 491.

Jamaica A (ca. summer 1668)

Location: Adversaria 1661, pp. 215-219, 232-252.

Description: A letter from Benjamin Worsley to an unidentified correspondent (probably Buckingham), giving advice on the Jamaican sugar trade, probably dating from summer 1668. The letter was copied by Locke at an unknown date into his “Adversaria 1661” commonplace book, with the marginal caption “Jamaica”. In this listing, the letter is titled “Jamaica A” to distinguish it from the second letter dated 24 February 1669.

Publications: None

Discussions: Leng, Benjamin Worsley, 148, 205.

Plantations A (14 August 1668)

Location: Adversaria 1661, pp. 16-17, 158-171.

Description: A paper written by Benjamin Worsley addressed to Lord Ashley, arguing the advantages of foreign plantations. The paper is dated 14 August 1668 and headed “The peculiar advantages which this nation hath by the trade of our plantations”. There are three copies: (1) in the Shaftesbury papers, with corrections by Worsley [National Archives 30/24/49, ff. 221-227]; (b) in the papers of Secretary of State Arlington [British Library, MS. Rawlinson A478, ff. 65-72]; and (c) in Locke’s “Adversaria 1661” commonplace book, with the marginal caption “Plantations” (the date of this copy is unknown). In this listing, the letter is titled “Plantations A” to distinguish it from the later letter to Buckingham with the same caption.

Publications: None

Discussions: Leng, Benjamin Worsley, 148, 205.

Queries on Scottish church government (1668)

Location: Public Record Office, London, PRO 30/24/47/30, f. 45.

Description: A set of queries written in Locke’s hand, endorsed “Q Church governm^t Concerning the Scotch Discipline 68”. Written on a single sheet of paper, c. 227 × 169 mm (edges damaged and repaired).

Publications:

An essay concerning toleration and other writings on law and politics, 1667-1683 / John Locke ; edited with an introduction, critical apparatus, notes and transcription of ancillary manuscripts by J.R. Milton and Philip Milton. – Oxford : Clarendon Press, 2006. – (The Clarendon edition of the works of John Locke). – p. 319-321.

Discussions: Milton & Milton, Introduction to publication #1 above, p. 53-57, 192.

Some of the consequences that are like to follow upon lessening of interest to 4 per cent (1668)

Location:

Bodleian Library, MS. Locke e. 8
[fair copy (ff. 3-17^v) with a Supplement added in 1668 (ff. 18-27^v) and some additional material from 1674 (ff. 28-31^v); includes additions and corrections by Locke]
British Library, Add. MS. 32,094, ff. 289-293
[copy of the original paper made for Sir William Coventry]
Bodleian Library, MS. Locke b. 3, ff. 2-3^v
[a quire from Locke’s autograph of the 1668 Supplement; f. 1 also contains a shorthand fragment endorsed “Usury 4 per Cent 68” which Kelly considers a draft for a dedication of the 1668 paper to Lord Ashley]
Bodleian Library, MS. Locke d. 2, ff. 28-37^v
[quires from Locke’s autograph of the 1674 additions, including a section (ff. 34^v-37^r) that continues the text of the fair copy]

Description: A paper on interest rates dating from 1668. A manuscript note on the Coventry copy (#2 above) states that the paper is “By Mr. Locke directed by Lord Ashley.” At the end of the original paper, Locke wrote “Sic cogitavit 1668 JL”. As noted above, Locke added a “Supplement” in 1668, and made further additions in 1674. Patrick Kelly refers to the entire series of papers as “Early writings on interest”.

The debate on the official rate of interest was revived in the 1690s, and Locke recast the paper to form the core of his Some considerations of the consequences of the lowering of interest, and raising the value of money (1691). Indeed, the quires from Locke’s autographs additions in 1674 in MS. Locke d. 2 have been incorporated into Locke’s manuscript of Some considerations.

Publications:

[modernized text of the fair copy:] “Locke’s early MS. on interest”. // IN: The origins of scientific economics / William Letwin (1963). – p. 295-323.
[the complete Early writings on interest:] Locke on money / John Locke ; edited … by Patrick Hyde Kelly. – Oxford : Clarendon Press, 1991. – (The Clarendon edition of the works of John Locke). – p. 167-202.

Discussions: Kelly, “Texual introduction” to publication #2 above, p. 122-125.

Anatomia (1668 after December 15)

Location: Public Record Office, London, PRO 30/24/47/2, ff. 31-38^v.

Description: The manuscript is written in Locke’s hand, apart from the first sentence written by Sydenham and probably after the remainder had been written. [In top and left margin] There are extensive corrections in Locke’s hand. The manuscript is endorsed “Anatomia 68”. [Dewhurst (publications #1 & 2) inaccurately transcribes this as “Anatomie”.] Internal evidence suggests that it was written after 14 December 1668; it was probably completed by February 1668/9.

The authorship has been in dispute. Dewhurst considers that the work was “written in collaboration with Dr. Thomas Sydenham”, whereas Guy Meynell and Jonathan Walmsley argue that Locke was the author. Meynell suggests that this paper, and “De arte medica” (1669) were drafts for a preface to Sydenham’s “Medical observations” [Royal College of Physicians of London, MS. 572]. Anstey and Burrows (2009) provide definitive arguments for Locke’s authorship.

The manuscript consists of four sheets of paper, each folded once to form a total of 16 pages. The size of the pages differs slightly: ca. 225 × 160 mm.

Publications:

“Locke and Sydenham on the teaching of anatomy” / by Kenneth Dewhurst. // IN: Medical history. – 2 (1958):1-12. – The text appears on p. 3-8; Dewhurst’s transcription is often inaccurate and does not include Locke’s corrections and deletions.
Dr. Thomas Sydenham (1624-1689), his life and original writings / Kenneth Dewhurst. – London : Wellcome Historical Medical Library, 1966. – p. 85-93.
“Las ideas antianatómicas y antimicroscópicas de Thomas Sydenham” / Miguel Sánchez González. // IN: Asclepio. – 40:fasc. 1 (1988):252-263.
John Locke’s natural philosophy (1632-1671) / Jonathan Craig Walmsley. – Thesis (Ph.D.)–King’s College London, 1998. – leaves 277-290.
“John Locke’s ‘Anatomia’ and ‘De arte medica’ : new transcriptions” / Craig Walmsley. – Drafted circa 1998-2005; posted March 25, 2014. – Revision of #4.
Writings on medicine and natural philosophy / John Locke ; edited by Peter Anstey and Lawrence Principe. – Oxford : Clarendon Press, in preparation. – (The Clarendon edition of the works of John Locke)
[Spanish translation]: Ensayo sobre la anatomía / Thomas Sydenham y John Locke ; traducción y introducción de Miguel Ángel Sánchez González. – Oviedo : KRK, 2009. – 92 pages. – (Cuadernos de pensamiento ; 2)

Discussions: General: Dewhurst (publications #1 and 2 above); Walmsley (publication #4 above); authorship: Guy Meynell, “Locke as author of Anatomia and De arte medica” (1994); Peter Anstey and John Burrows, “John Locke, Thomas Sydenham, and the authorship of two medical essays” (2009).

Plantations B (18 December 1668)

Location: Adversaria 1661, pp. 172-179.

Description: A letter from Benjamin Worsley to Buckingham, dated 18 December 1668, relating to Jamaican privateers. The letter was copied by Locke at an unknown date into his “Adversaria 1661” commonplace book, with the marginal caption “Plantations” and headed “A copy of my first letter to the duke of Buckingham about the privateers communicated alsoe to my Lord Keeper, Lord Arlington, and some others of his majesties privy councell”. Another copy of the letter, with alterations by Worsley, is in the papers of Secretary of State Arlington [British Library, MS. Rawlinson A478, ff. 61-62], titled “Considerations about the Jamaican privateers”. The letter is listed here as “Plantations B” to distinguish it from the earlier paper addressed to Shaftesbury.

Publications: None

Discussions: Leng, Benjamin Worsley, 205.

Tussis [between 1668 and 1670?]

Location: Public Record Office, London, PRO 30/24/47/2, ff. 75-78;
copy in Bodleian Library, MS. Locke c. 42A, pp. 258-264.

Description: A paper on coughs in Locke’s hand, titled “Tussis”. It breaks off abruptly and is followed by a sentence written by Dr. Thomas Sydenham, the author of the paper. The manuscript consists of two sheets of paper, each folded once to form 8 pages, c. 300 × 205 mm. Fols. 77^v-78^v are blank.

Locke later copied the paper into one of his medical commonplace books, including some additional observations before and after the essay.

Publications:

[The PRO MS. only:] “An essay on coughs by Locke and Sydenham” / by Kenneth Dewhurst. // IN: Bulletin of the history of medicine. – 33 (1959):368-372.
Dr. Thomas Sydenham (1624-1689), his life and original writings / Kenneth Dewhurst. – London : Wellcome Historical Medical Library, 1966. – p. 94-100.

Arthritis Q [ca. 1668]

Location: Bodleian Library, MS. Locke d. 9, p. 51.

Description: Queries in Locke’s hand, with the marginal caption “Arthritis Q”, and intialed by Locke. The note is undated, possibly written ca. 1668.

Publications: None

Calculus [ca. 1668]

Location: Bodleian Library, MS. Locke d. 9, p. 81.

Description: A note in Locke’s hand, with the marginal caption “Calculus”, and intialed by Locke. The note is undated, but was probably written ca. 1668.

Publications: None

Pulsus Q [ca. 1668]

Location: Bodleian Library, MS. Locke d. 9, p. 110.

Description: Queries in Locke’s hand, with the marginal caption “Pulsus Q”, and intialed by Locke. The note is undated, possibly written ca. 1668.

Publications: None

Ireland (unknown)

Location: Adversaria 1661, pp. 220-231.

Description: An undated report from the Council of Trade and Plantations, presumably compiled by Benjamin Worsley, copied by Locke at an unknown date into his “Adversaria 1661” commonplace book, with the marginal caption “Ireland” and the heading “The state of Ireland in reference to trade”.

Publications: None

Discussions: Leng, Benjamin Worsley, 169.

Index to Lips, Method medendi, 1668 [1668 or later]

Location: Bodleian Library, MS. Locke d. 9, pp. 154/155.

Description: An index in Locke’s hand, to “Method medendi probata a G... Lips 1668”.

Publications: None

Contents

Name Index

Title Index


John Locke Manuscripts
John Locke Bibliography	John Locke Chronology	John Locke Resources